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Psychedelic Information Theory

Shamanism in the Age of Reason

Search Results : dopamine

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Informal Discussion of Topics

... system of perception, modulated by serotonin and dopamine. This complex interference pattern is what I am describing with the Control Interrupt Model of psychedelic action. According to PIT, each hallucinogen creates a slightly different tremor or v...

Functional selectivity and classical concepts of quantitative pharmacology

... phenomenon are presented from serotonin, opioid, dopamine, vasopressin, and adrenergic receptor systems. A variety of mechanisms may influence this apparently ubiquitous phenomenon. It may be initiated by differences in ligand-induced intermediate c...

Physical Shamanism and Shamanic Therapy

... and cellular signaling are modulated by 5-HT and dopamine, interrupting these signaling pathways will not only produce patterns of spontaneous neural organization, they will also produce patterns of spontaneous metabolic and cellular organization. F...

The Case Against the Spirit Model of Psychedelic Action

... many models of psychosis offered, including the dopamine model of psychosis, the cholinergic model of mediating waking/dreaming states, and the Ketamine/NMDA model of schizophrenia. Hallucinations, mystical experience, and delusions of grandeur are...

Topographic pharmaco-EEG mapping of the effects of the South American psychoactive beverage ayahuasca in healthy volunteers

... of effects shown by pro-serotonergic and pro-dopaminergic drugs. The q-EEG profile supports the role of 5-HT2 and dopamine D2-receptor agonism in mediating the effects of ayahuasca on the central nervous system....

An Interview with Dave Nichols

... the receptor, and some of the other receptors, dopamine receptors, and some of the other serotonin receptors. I think that's really an interesting area to look at. We've done some work already with another serotonin receptor called the 5HT1A recep...

Psychedelic Pharmacology

... adrenaline (epinephrine), norepinephrine, and dopamine (DA), and all of these chemicals are classified as amines, meaning that they have a nitrogen (N+) containing amino group hanging off a root carbon ring. This nitrogen structure is the key ele...

From drugs to deprivation: a Bayesian framework for understanding models of psychosis

... serotonergic hallucinogens, cannabinoids and dopamine agonists. Conclusion By acknowledging the importance of perception and perceptual aberration in mediating the positive symptoms of psychosis, the model also provides a useful setting in w...

Presynaptic regulation of recurrent excitation by D1 receptors in prefrontal circuits

... activity in prefrontal neurons is modulated by dopamine. To examine the mechanisms by which dopamine might modulate transmission in local excitatory circuits, we have performed dual whole-cell recordings in connected pyramidal cell pairs with and ...

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