Psychedelic Information Theory
Shamanism in the Age of Reason
Search Results : disinhibition
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5-HT2A Agonism and Multisensory Binding
... 5-HT2A receptor agonists (hallucinogens) promote disinhibition and excitability in 5-HT mediated pathways, indicating that psychedelic action is the product of spontaneous nonlinear feedback excitation in the recurrent circuits responsible for real-...
... within cortical circuits.3 The level of disinhibition and drift in the visual field is proportional to the dose of hallucinogen, and this assumption is proved correct by individual reports of hallucinogen use. While at lower doses there may...
Presynaptic uptake blockade hypothesis for LSD action at the lateral inhibitory synapse in Limulus
We investigated the action of LSD at the putative indoleaminergic lateral inhibitory synapse in the lateral eye of Limulus polyphemus. We recorded extracellular and intracellular voltage responses from eccentric cells while producing inhibition eithe...
... Agonistic interference at 5-HT subtypes promotes disinhibition and extreme excitability between feedback-coupled autonomic neural assemblies in the cortex, midbrain, and brainstem. Excitation in the autonomic neural assemblies which process sensatio...
EEG coherence in post-LSD visual hallucinations
... state, but localized and isolated occipital disinhibition upon eye closure, a state known to facilitate hallucinatory experiences. An analogy is drawn to findings in the interictal and ictal epileptic focus. In HPPD, we speculate that occipital...
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