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Psychedelic Information Theory

Shamanism in the Age of Reason

Search Results : brain

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Informal Discussion of Topics

... fractal patterns created on the surface of their brains onto the surfaces of their bodies, their artwork, their walls, and their world. The physical spilling over of complex psychedelic patterns from a single underlying ripple effect is the foundati...

A Single Dose of Lysergic Acid Diethylamide Influences Gene Expression Patterns within the Mammalian Brain

... by acute LSD administration in the mammalian brain. These studies represent a novel approach to elucidate the mechanism of action of this class of drugs. We have identified a number of genes that are predicted to be involved in the processes of ...

Reviews for Psychedelic Information Theory

... the visual information processing rate, and the brain's pattern-recognition function all come together (or come apart) to modulate entoptic (pattern overlay--"Patterns... Colors...") and eidetic (internal visual world--"Machine Elves") hallucinator...

PIT Summary and Overview

... and consciousness. By modeling the human brain as a dynamical information processing system, PIT demonstrates how consciousness can be destabilized to produce multiple states at once, or multi-stability, which is subjectively perceived as ex...

Conclusions and Discussion

... First and foremost, PIT assumes that the human brain acts as a resonant oscillator, and that sensation, perception, and consciousness are the result of time-synchronized interference patterns of recurrent neural spike trains cascading through the ...

Rapid erasure of long-term memory associations in the cortex by an inhibitor of PKM zeta

... subserve long-term memory persistence in the brain. The components of the remodeled synaptic machinery, and how they sustain the new synaptic or cellwide configuration over time, are yet to be elucidated. In the rat cortex, long-term associative...

Kappa Opioid Receptor Activation of p38 MAPK Is GRK3- and Arrestin-dependent in Neurons and Astrocytes

... suggest that KOR may activate p38 MAPK in brain by a GRK3 and arrestin-dependent mechanism....

A systems model of altered consciousness: integrating natural and drug-induced psychoses

Increasing evidence from neuroimaging and behavioral studies suggests that functional disturbances within cortico-striato-thalamic pathways are critical to psychotic symptom formation in drug-induced and possibly also naturally occurring psychoses. R...

Serotonin, via 5-HT2A receptors, increases EPSCs in layer V pyramidal cells of prefrontal cortex by an asynchronous mode of glutamate release

... This paradox prompted us to investigate (in rat brain slices) whether 5-HT was acting through an atypical mode of excitatory transmitter release. We found that the frequency of 5-HT-induced spontaneous EPSCs was fully supported by Sr2+ in the absen...

Serotonin and brain: evolution, neuroplasticity, and homeostasis

... helps appreciate its holistic actions on brain homeostasis. In plants serotonin and its allied indole-containing molecules 5-hydroxytryptophan, auxin, and melatonin regulate many of the processes involved in cell diVerentiation: mitosis, m...

5-HT2A Agonism and Multisensory Binding

... cerebellum, the hippocampus, thalamic nuclei, brainstem nuclei, sensory neurons, platelets, fibroblasts, intestines, smooth muscles, and cardiovascular systems.3,4,5,6 By following the pathways of 5-HT2A modulated signal transduction through the ...

Serotonin Induces Excitatory Postsynaptic Potentials in Apical Dendrites of Neocortical Pyramidal Cells

By intracellular and whole cell recording in rat brain slices, it was found that bath-applied serotonin (5-HT) produces an increase in the frequency and amplitude of spontaneous excitatory postsynaptic potentials/currents (EPSPs/EPSCs) in layer V pyr...

Hallucinogens

... and lysergic acid diethylamide (LSD-25), early brain research focused intensely on the possibility that LSD or other hallucinogens had a serotonergic basis of action and reinforced the idea that 5-HT was an important neurotransmitter in brain. The...

Serotonin 5-Hydroxytryptamine2A Receptor Activation Suppresses Tumor Necrosis Factor-α-Induced Inflammation with Extraordinary Potency

... receptor is primarily recognized for its role in brain neurotransmission, where it mediates a wide variety of functions, including certain aspects of cognition. However, there is significant expression of this receptor in peripheral tissues, where i...

Crude cognitive schematic of waking consciousness

... that follows perceptual signal through the brain. Starting at the left with the two inputs (audio and visual) you can chart the flow of signal through the various processing levels until you ultimately arrive at output, or behavior, with a del...

Replicable functional magnetic resonance imaging evidence of correlated brain signals between physically isolated subjects.

... correlated neural signals may be detected in the brains of individuals who are physically and sensorily isolated from each other. Functional MRI and EEG methods were used in the present study in an attempt to replicate these findings. DESIGN/SETTING...

Spirits and Spiritual Communion

... symptom of insanity. According to PIT, when the brain destabilizes due to hallucinogenic interrupt it will naturally seek coherence with the strongest local periodic driver. In some cases the strongest local driver may be the shaman, it may be the ...

Psychic Bonding and Psi

... example of stress creating a situation where the brain is ripe for entrainment and imprinting. A romantic version of group mind leading to psychic bonding might happen spontaneously on date when two potential mates sit and talk quietly for long pe...

Hypnotic Entrainment and Induced Trance States

... out at maximum amplitudes. If we envision the brain as an oscillator for maintaining stable consciousness, each band of consciousness in the spectrum must therefore have its own corresponding resonant frequency or frequencies which can drive spon...

Physical Shamanism and Shamanic Therapy

... 5-HT receptors in the gut as well as the brain before metabolic homeostasis can be fully uncoupled and re-tuned. Techniques of dieting and fasting merely speed and amplify the overall destabilizing effect of psychedelics on global metabolic ...

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